The Inner Space Center (ISC) at the University of Rhode Island Graduate School of Oceanography serves as the shore-based telepresence hub or "mission control" for multiple ships of exploration, including E/V Nautilus. The ISC is connected to Internet2, which permits high bandwidth streams of video, audio, and data to flow from the ship to shore where it is captured, displayed and disseminated in real time. The Inner Space Center also hosts teams of scientists and engineers during operations, so they can communicate with their counterparts at sea and monitor the expedition in real time.
The ISC is the streaming and quality control provider for the live E/V Nautilus video streams. The ISC maintains the master archive of all E/V Nautilus video and data, and is the distributor of video and data to local and foreign scientists.